Antenatal Corticosteroid Therapy to Prevent Neonatal Respiratory Distress Syndrome / 대한주산의학회잡지
Korean Journal of Perinatology
;
: 178-185, 1997.
Article
in Korean
| WPRIM
| ID: wpr-75646
ABSTRACT
OBJECTIVES:
Our purpose was to determine the efficacy of maternal corticosteroid therapy in the prevention of neonatal respiratory distress syndrome. STUDYDESIGN:
The data in this study was taken from 136 women who participated in prematurity prevention programs at two hospital. Of 136 women who were delivered at 25 to 34 weeks, 68 received dexamethasone and 68 did not. 'I'he frequency and relative risk of adverse outcomes, including repiratory distress syndrome, necrotizing enterocolitis, neonatal sepsis and maternal infection wcre compared by means of univariate techniques.RESULT:
When dexamethansone was administered, there was a lower incidence of respiratory distress syndrome at between 30 to 32 weeks gestation (relative risk of treatment group vs control group=0.425, p0.05). I'here was no statistical difference between 33 weeks to 34 weeks (relative risk of treatment group vs control group=0.782, p>0.05). 'I'here was no statistical significance in the incidence of maternal infection, neonatal sepsis or necrotizing enterocolitis (p=0.808, p=0.698, p=0.559).CONCLUSION:
Dexamethasone appears to significantly reduce neonatal respiratory distress syndrome at between 30 and 32 weeks gestation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Respiratory Distress Syndrome, Newborn
/
Dexamethasone
/
Incidence
/
Sepsis
/
Enterocolitis, Necrotizing
Type of study:
Etiology study
/
Incidence study
/
Prognostic study
Limits:
Female
/
Humans
/
Pregnancy
Language:
Korean
Journal:
Korean Journal of Perinatology
Year:
1997
Type:
Article
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