Research progress in host-related diagnostic markers for hepatitis B virus infection / 中华检验医学杂志

ABSTRACT

Chronic hepatitis B is caused by infection with hepatitis B virus (HBV), which can lead to the development of cirrhosis and primary hepatocellular carcinoma. Viral persistence and clinical outcomes after HBV infection depend on viral factors and host factors. With the rapid development of the invasion mechanism of HBV infection, host?related genes and proteins involved in HBV infection have been found and used as new diagnostic markers both in the treatment evaluation and prognosis of HBV infection. This review mainly introduces the clinical application and related progress of laboratory serum markers in chronic HBV infection based on host factors for optimizing clinical diagnosis.