Quantitative analysis of the effect of surface treatments and designs intraocular lenses on posterior capsular opacity / 国际眼科杂志(Guoji Yanke Zazhi)

ABSTRACT

@#AIM: To quantitatively compare the effects of different surface treatments and designs of intraocular lens(IOL)on posterior capsule opacification(PCO)using EPCO2000.<p>METHODS: A retrospective study was conducted to observe 600(971 eyes)age-related cataract patients after 1a of phacoemulsification with implantation of intraocular lens in our hospital from March to November 2016. Patients were divided into 4 groups based on the type of IOL implant 43 eyes in ZCB00 group, 365 eyes in ZA9003 group, 340 eyes in HQ-201HEP group and 223 eyes in Human Optics group. Retroillumination slit-lamp photographs were taken after the pupil was fully dilated and the degree of PCO was scored by EPCO2000 and compared among the groups.<p>RESULTS: There were 167 eyes(17.2%)with PCO involving the central 3mm of the pupil and 78 eyes(8.0%)with significant PCO or NdYAG laser capsulotomy. According to the hydrophobicity of IOL optical surface materials, the total score of hydrophobic group 0.000(0.000, 0.012)was obviously lower than that of hydrophilic group 0.127(0.056, 0.242)(<i>P</i><0.05). The total score of heparin-free group 0.127(0.056, 0.242)was lower than that of heparin-modified group 0.175(0.067, 0.371), and the difference was statistically significant(<i>P</i><0.05). The total score of single-piece group 0.000(0.000, 0.012)was obviously lower than that of three-piece group 0.120(0.041, 0.247)(<i>P</i><0.05). According to the different haptic angular magnitude of IOL, the total score of the 0° haptic anglulation group 0.107(0.000, 0.212)was lower than that of the 5° haptic anglulation group 0.142(0.051, 0.298), and the difference was statistically significant(<i>P</i><0.05).<p>CONCLUSION: A single-piece, square-edged, hydrophobic acrylic IOL can reduce PCO formation more effectively.