Relationship between the diameter of the central retinal artery equivalent and the arteriole-to-venule ratio to arteriosclerosis / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science
;
(12): 1922-1927, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-756887
ABSTRACT
@#AIM:
To investigate the effect of retinal vascular diameter on arterial stiffness of the participants stratified by age.<p>METHODS:
Participants who took part in the 2014(fourth)physical examination and brachial-ankle pulse wave velocity(baPWV)and fundus color photography were observed. According to the WHO criteria of age, participants were divided into 3 groups by age 18-44 years old group, 45-59 years old group and above 60 years old group. Multiple linear regression analysis was used to analyze the association between central retinal artery equivalent(CRAE)and arteriole-to-venule ratio(AVR)with baPWV in the total participants and then stratified by age. Multivariate Logistic regression model was use to analysis the influence of CRAE on arteriosclerosis(baPWV≥14.00m/s)in the total participants and then stratified by age.<p>RESULTS:
CRAE and AVR decrease with age, in the non-atherosclerotic people. In multivariate linear regression analysis, CRAE and AVR were defeat correlated with baPWV in the 45-59 years old group and above 60 years old group. For each increase of 1 unit of CRAE and AVR, baPWV decreased by 0.01m/s, 0.02m/s, 1.99m/s and 5.58m/s, respectively. In multivariate Logistic regression analysis, the risk of arteriosclerosis decreased with the increase of CRAE by 1μm in the 45-59 years group and above 60 years old group. The <i>OR</i> values(95% <i>CI</i>)were 0.99(0.98-0.99)and 0.98(0.97-0.99), respectively.<p>CONCLUSION:
In the 45-59 years old group and above 60 years old group, CRAE and AVR were negatively correlated with arterial stiffness, and their increase was the protective factor of arteriosclerosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
International Eye Science
Year:
2019
Type:
Article
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