Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapy
Protein & Cell
;
(12): 246-250, 2012.
Article
in English
| WPRIM
| ID: wpr-757286
ABSTRACT
Recent advances in the study of human hepatocytes derived from induced pluripotent stem cells (iPSC) represent new promises for liver disease study and drug discovery. Human hepatocytes or hepatocyte-like cells differentiated from iPSC recapitulate many functional properties of primary human hepatocytes and have been demonstrated as a powerful and efficient tool to model human liver metabolic diseases and facilitate drug development process. In this review, we summarize the recent progress in this field and discuss the future perspective of the application of human iPSC derived hepatocytes.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Therapeutics
/
Transplantation
/
Cell Differentiation
/
Hepatocytes
/
Cell Biology
/
Drug Evaluation, Preclinical
/
Induced Pluripotent Stem Cells
/
Cell- and Tissue-Based Therapy
/
Liver Diseases
/
Models, Biological
Limits:
Humans
Language:
English
Journal:
Protein & Cell
Year:
2012
Type:
Article
Similar
MEDLINE
...
LILACS
LIS