Theoretical and simulation studies on voltage-gated sodium channels
Protein & Cell
;
(12): 413-422, 2015.
Article
in English
| WPRIM
| ID: wpr-757584
ABSTRACT
Voltage-gated sodium (Nav) channels are indispensable membrane elements for the generation and propagation of electric signals in excitable cells. The successes in the crystallographic studies on prokaryotic Nav channels in recent years greatly promote the mechanistic investigation of these proteins and their eukaryotic counterparts. In this paper, we mainly review the progress in computational studies, especially the simulation studies, on these proteins in the past years.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Permeability
/
Substrate Specificity
/
Ion Channel Gating
/
Chemistry
/
Voltage-Gated Sodium Channels
/
Ligands
/
Metabolism
/
Models, Biological
Language:
English
Journal:
Protein & Cell
Year:
2015
Type:
Article
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