The late stage of autophagy: cellular events and molecular regulation
Protein & Cell
;
(12): 907-915, 2010.
Article
in English
| WPRIM
| ID: wpr-757687
ABSTRACT
Autophagy is an intracellular degradation system that delivers cytoplasmic contents to the lysosome for degradation. It is a "self-eating" process and plays a "house-cleaner" role in cells. The complex process consists of several sequential steps-induction, autophagosome formation, fusion of lysosome and autophagosome, degradation, efflux transportation of degradation products, and autophagic lysosome reformation. In this review, the cellular and molecular regulations of late stage of autophagy, including cellular events after fusion step, are summarized.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Autophagy
/
Lysosomes
/
Metabolism
Limits:
Animals
/
Humans
Language:
English
Journal:
Protein & Cell
Year:
2010
Type:
Article
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