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Cellular models for disease exploring and drug screening
Zhi-Kun LI; Qi ZHOU.
Protein & Cell ; (12): 355-362, 2010.
Article in English | WPRIM | ID: wpr-757755
ABSTRACT
The biopharmaceutical industry has been greatly promoted by the application of drug and disease models, including both animal and cellular models. In particular, the emergence of induced pluripotent stem cells (iPSC) makes it possible to create a large number of disease-specific cells in vitro. This review introduces the most widely applied models and their specialties.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Therapeutics / Neurodegenerative Diseases / Cell Biology / Drug Evaluation, Preclinical / Induced Pluripotent Stem Cells / Methods / Models, Biological Type of study: Diagnostic study / Screening study Limits: Animals / Humans Language: English Journal: Protein & Cell Year: 2010 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Therapeutics / Neurodegenerative Diseases / Cell Biology / Drug Evaluation, Preclinical / Induced Pluripotent Stem Cells / Methods / Models, Biological Type of study: Diagnostic study / Screening study Limits: Animals / Humans Language: English Journal: Protein & Cell Year: 2010 Type: Article