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Prognostic value of right pulmonary artery distensibility in dogs with pulmonary hypertension
Journal of Veterinary Science ; : e34-2019.
Article in English | WPRIM | ID: wpr-758931
ABSTRACT
The right pulmonary artery distensibility (RPAD) index has been used in dogs with pulmonary hypertension (PH) caused by heartworm infection, myxomatous mitral valve disease, or patent ductus arteriosus. We hypothesized that this index correlates with the tricuspid regurgitation pressure gradient (TRPG) assessed by echocardiography and could predict survival in dogs with PH secondary to various causes. To assess this hypothesis, the medical records of 200 client-owned dogs at a referral institution were retrospectively reviewed. The RPAD index and the ratios of acceleration time to peak pulmonary artery flow (AT) and to the ejection time of pulmonary artery flow (ET) were recorded for each dog. The owners were contacted for follow-up assessments. The findings indicated that the RPAD index was correlated with the TRPG (R2 = 0. 362, p < 0.001). The survival time was significantly shorter in dogs with an RPAD index ≤ 21% that were followed up for 3 months and in dogs with an RPAD index ≤ 24% that were followed up for 1 year. Thus, the RPAD index was correlated with the TRPG and could predict the clinical outcome in dogs with PH caused by various diseases. This index could be used to evaluate the severity of PH in dogs without tricuspid regurgitation.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pulmonary Artery / Referral and Consultation / Tricuspid Valve Insufficiency / Echocardiography / Medical Records / Retrospective Studies / Follow-Up Studies / Ductus Arteriosus, Patent / Acceleration / Hydrogen-Ion Concentration Type of study: Observational study / Prognostic study / Risk factors Limits: Animals Language: English Journal: Journal of Veterinary Science Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pulmonary Artery / Referral and Consultation / Tricuspid Valve Insufficiency / Echocardiography / Medical Records / Retrospective Studies / Follow-Up Studies / Ductus Arteriosus, Patent / Acceleration / Hydrogen-Ion Concentration Type of study: Observational study / Prognostic study / Risk factors Limits: Animals Language: English Journal: Journal of Veterinary Science Year: 2019 Type: Article