Weak D type 33 Found in a Patient with a Weak D Phenotype: The First Case in Korea / 대한수혈학회지
Korean Journal of Blood Transfusion
; : 65-70, 2019.
Article
in Ko
| WPRIM
| ID: wpr-759578
Responsible library:
WPRO
ABSTRACT
RHD genotyping is a useful adjunct to serologic testing. Although the use of RHD genotyping in the detection of Asia type DEL in serological D negative Koreans is gradually increasing, it is rarely requested for patients with a known weak D phenotype. This paper reports the first Korean case of a 52-year-old female patient with serologic weak D phenotype and weak D type 33 (c.520G>A at exon 4 of RHD) identified by RHD exon 1 to 10 sequencing. In silico analysis predicted that the RHD c.520G>A (V174M) results in a serologic weak D phenotype.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Phenotype
/
Asia
/
Computer Simulation
/
Serologic Tests
/
Exons
/
Korea
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
Ko
Journal:
Korean Journal of Blood Transfusion
Year:
2019
Type:
Article