Bilateral Segmental Neurofibromatosis with Lentiginosis Showing a Checkerboard Pattern / 대한피부과학회지
Korean Journal of Dermatology
;
: 328-331, 2019.
Article
in English
| WPRIM
| ID: wpr-759746
ABSTRACT
Segmental neurofibromatosis, a subtype of neurofibromatosis type 1, is characterized by neurofibromas and/or café-au-lait spots limited to an area or segment of the body. Checkerboard pattern is a rare type of cutaneous mosaic manifestation, characterized by squares or broad ribbons of affected skin with sharp demarcation at the midline. Herein, we report the case of a patient with bilateral segmental neurofibromatosis with lentiginosis showing a checkerboard pattern. Our patient had multiple hyperpigmented macules on her entire body in a checkerboard pattern since birth. Several café-au-lait patches were observed on the left buttock and right axilla. A neurofibroma was incidentally found beneath the café-au-lait patch by histological examination, which showed ill-defined spindle cells with elongated nuclei at the deep dermis that stained positive for S-100. Based on the clinical presentation and histopathologic results, the patient was diagnosed with bilateral segmental neurofibromatosis with lentiginosis showing a checkerboard pattern.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin
/
Axilla
/
Buttocks
/
Neurofibromatosis 1
/
Neurofibromatoses
/
Body Patterning
/
Dermis
/
Parturition
/
Lentigo
/
Neurofibroma
Limits:
Humans
Language:
English
Journal:
Korean Journal of Dermatology
Year:
2019
Type:
Article
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