Spatial and Temporal Characteristics of Visual Field Progression in Glaucoma Assessed by Parallel Factor Analysis
Korean Journal of Ophthalmology
;
: 279-286, 2019.
Article
in English
| WPRIM
| ID: wpr-760023
ABSTRACT
PURPOSE:
To explore spatial and temporal characteristics of glaucomatous visual field (VF) progression through multi-way decomposition of data.METHODS:
Six serial VF exams with intervals of 6.0 ± 1.0 months in 121 pre-perimetric glaucoma eyes and 80 perimetric glaucoma eyes were arranged into a three-dimensional cube. The data were decomposed using parallel factor analysis.RESULTS:
Three tri-linear components (i.e., spatial scores, temporal loadings, and subject-specific loadings) were identified. Component 1 clearly showed differences between superior and inferior hemispheres, linear trends over time, and wide variability in perimetric glaucoma. Findings were compatible with well-known characteristics of glaucomatous VF defects. Component 2 showed nasal and central areas in contrast with superior, inferior, and temporal peripheral locations, whereas component 3 showed a contrast between nasal and temporal hemispheres. Both components 2 and 3 failed to show clear temporal trends.CONCLUSIONS:
Identification of spatio-temporal patterns shows new possibilities for a multi-way decomposition methodology for earlier diagnosis and prediction of glaucomatous VF progression.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Visual Fields
/
Glaucoma
/
Factor Analysis, Statistical
/
Diagnosis
Type of study:
Diagnostic study
/
Prognostic study
Language:
English
Journal:
Korean Journal of Ophthalmology
Year:
2019
Type:
Article
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