Complete Remission of Metastatic Duodenal Neuroendocrine Carcinoma Treated with Chemotherapy and Surgical Resection / 대한췌담도학회지
Korean Journal of Pancreas and Biliary Tract
;
: 121-126, 2019.
Article
in Korean
| WPRIM
| ID: wpr-760172
ABSTRACT
A 57-year-old male with periampullary duodenal mass was diagnosed as grade 3 duodenal neuroendocrine carcinoma with multiple liver metastasis. After nine cycles of cisplatin and etoposide, abdominal computed tomography (CT) findings showed complete regression of primary duodenal mass with marked size reduction of liver metastasis. Positron emission tomography findings showed metabolic complete response in both duodenal and liver mass. Pylorus-preserving pancreaticoduodenectomy was done and pathologic finding showed 5 mm sized remnant neuroendocrine tumor. The patient has remained alive with no evidence of disease for 43 months after initial diagnosis. This case suggests the possibility of heterogeneous nature of grade 3 neuroendocrine carcinoma and selected population may have extreme sensitivity to cisplatin and etoposide chemotherapy leading to complete response.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Cisplatin
/
Pancreaticoduodenectomy
/
Neuroendocrine Tumors
/
Carcinoma, Neuroendocrine
/
Positron-Emission Tomography
/
Diagnosis
/
Drug Therapy
/
Etoposide
/
Liver
/
Neoplasm Metastasis
Type of study:
Diagnostic study
Limits:
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Pancreas and Biliary Tract
Year:
2019
Type:
Article
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