The role of Lactobacillus reuteri DSM 17938 for the absorption of iron preparations in children with iron deficiency anemia / 소아과
Korean Journal of Pediatrics
;
: 173-178, 2019.
Article
in English
| WPRIM
| ID: wpr-760202
ABSTRACT
PURPOSE:
To determine whether Lactobacillus reuteri DSM 17938 plays a role in absorption of iron preparations given to children with iron deficiency anemia (IDA).METHODS:
We performed a quasi-experimental study involving pre- and postintervention tests using a control group in North Sulawesi province, Indonesia, between July and September 2017. We conducted a single-blind controlled trial that included primary school children who were diagnosed with IDA based on reticulocyte hemoglobin equivalent (Ret-He) levels <27.8 pg/L.RESULTS:
A total of 66 children were randomized into 2 groups. Thirty-four children received iron preparations with the addition of L. reuteri DSM 17938 (group 1), whereas the other 32 received iron preparations alone (group 2). The baseline Ret-He levels before intervention were similar in both groups. After 14 days of intervention, mean Ret-He level in group 1 changed from 24.43±1.64 to 28.21±1.72 pg/L (P=0.000). Mean Ret-He level in group 2 changed from 24.31±1.42 to 27.03±2.14 pg/L (P=0.000). Statistical analysis showed a significant increase in Ret-He levels in both groups; Ret-He levels were significantly higher in the experimental group than in the control group (P<0.05).CONCLUSION:
Children with IDA receiving iron preparations with L. reuteri DSM 17938 for 14 days show higher Ret-He levels than those receiving iron preparations alone.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Reticulocytes
/
Anemia, Iron-Deficiency
/
Absorption
/
Limosilactobacillus reuteri
/
Non-Randomized Controlled Trials as Topic
/
Indonesia
/
Anemia
/
Iron
/
Lactobacillus
Type of study:
Controlled clinical trial
Limits:
Child
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Korean Journal of Pediatrics
Year:
2019
Type:
Article
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