Diels-Alder Type Adducts from Hairy Root Cultures of Morus macroura
Natural Product Sciences
;
: 233-237, 2019.
Article
in English
| WPRIM
| ID: wpr-760567
ABSTRACT
Three Diels-Alder type adducts, guangsangon E (1), chalcomoracin (2) and sorocein I (3) were isolated from hairy root cultures of Morus macroura. The structures of the isolated compounds (1 – 3) were determined by spectroscopic method (NMR and MS), and spectral comparison to literature. Cytotoxic activities of the isolated compounds (1 – 3) were investigated against P-388 murine leukemia cell line. Guangsangon E (1) showed the most potent cytotoxicity against P-388 murine leukemia cell line with IC₅₀ value of 2.75 ± 0.32 µg/mL. To the best of our knowledge, guangsangon E (1) and sorocein I (3) were reported for the first time from the tissue cultures of M. macroura.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Leukemia
/
Cell Line
/
Inhibitory Concentration 50
/
Morus
/
Methods
Language:
English
Journal:
Natural Product Sciences
Year:
2019
Type:
Article
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