The Occurrence and Risk Assessment of Exposure to Aflatoxin M₁ in Ultra-High Temperature and Pasteurized Milk in Hamadan Province of Iran
Osong Public Health and Research Perspectives
;
(6): 228-233, 2019.
Article
in English
| WPRIM
| ID: wpr-760709
ABSTRACT
OBJECTIVES:
Aflatoxins are a category of poisonous compounds found in most plants, milk and dairy products. The present research was carried out to detect the presence of aflatoxin M₁ (AFM₁) in samples of milk collected from Hamadan province, Iran.METHODS:
Twenty five samples of ultra-high temperature (UHT) and 63 samples of pasteurized milk were collected and the amount of AFM₁ was measured by an Enzyme-Linked Immunosorbent Assay method. In addition, the estimated daily intake (EDI) and hazard index (HI) of AFM₁ was determined by the following equations(EDI= mean concentration of AFM₁ × daily consumption of milk/body weight; HI=EDI/Tolerance Daily Intake).RESULTS:
AFM₁ was detected in 21 (84%) UHT milk samples and in 55 (87.30%) pasteurized milk samples. Seven (28%) samples of UHT and 21 (33.33%) pasteurized milk samples had higher AFM₁ content than the limit allowed in the European Union and Iranian National Standard Limits (0.05 μg/kg). None of the samples exceeded the US Food and Drug Administration limit (0.5 μg/kg) for AFM₁. EDI and HI for AM₁ through milk were 0.107 ng/kg body weight/day, and 0.535, respectively.CONCLUSION:
A significant percentage of milk produced by different factories in Iran (84% of UHT and 87.3% of pasteurized milk) was contaminated with AFM₁. Therefore, more control and monitoring of livestock feeding in dairy companies may help reduce milk contamination with AFM₁. As the HI value was lower than 1, it can be assumed that there was no risk of developing liver cancer due to milk consumption.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
United States Food and Drug Administration
/
Enzyme-Linked Immunosorbent Assay
/
Risk Assessment
/
Aflatoxins
/
Dairy Products
/
Milk
/
European Union
/
Livestock
/
Iran
/
Liver Neoplasms
Type of study:
Etiology study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Journal:
Osong Public Health and Research Perspectives
Year:
2019
Type:
Article
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