The Change of Urine Deoxypyridinoline in a Patient with Symptomatic Hypercalcemia associated with Hyperthyroidism / 대한골다공증학회지
Journal of Korean Society of Osteoporosis
;
: 193-198, 2011.
Article
in Korean
| WPRIM
| ID: wpr-760765
ABSTRACT
Malignancy and primary hyperparathyroidism are the common causes of hypercalcemia. Although hyperthyroidism may induce mild asymptomatic hypercalcemia, it is very rare that hyperthyroidism causes symptomatic hypercalcemia with a serum calcium concentration > or = 11 mg/dL. A 47-year-old woman visited our hospital for evaluation of nausea, vomiting, and urinary frequency. Her corrected total calcium level was 12.0 mg/dL. She was diagnosed with hyperthyroidism. We excluded the common causes of hypercalcemia by measurements of serum intact parathyroid hormone and a diagnostic work-up for malignancy. She was treated with propranolol and methimazole. The serum calcium and urine deoxypyridinoline, as a bone resorption marker, decreased and hypercalcemic symptoms resolved completely after restoration of the biochemical euthyroid state. In case of difficulty in excluding other causes of hypercalcemia in hyperthyroid patients, the follow-up of changes of bone turnover marker and level of serum calcium can be helpful.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Parathyroid Hormone
/
Propranolol
/
Vomiting
/
Bone Resorption
/
Calcium
/
Follow-Up Studies
/
Hyperparathyroidism, Primary
/
Amino Acids
/
Hypercalcemia
/
Hyperthyroidism
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
Language:
Korean
Journal:
Journal of Korean Society of Osteoporosis
Year:
2011
Type:
Article
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