Analysis of the Adherence in Once Yearly Intravenous Zoledronic Acid / 대한골다공증학회지

ABSTRACT

OBJECTIVES: We investigated drug adherence of once yearly intravenous bisphosphonate in patients with osteoporosis or osteoporotic fractures, and factors that influence their adherence. MATERIALS AND METHODS: Patients treated with once yearly intravenous bisphosphonate were asked about drug information and drug adherence using questionnaires. Factors related drug adherence were analyzed between non adherence group and adherence group. RESULTS: 65 patients (49.6%) were adherence group, 66 patients (50.3%) were included in non-adherence group. In group 1, were administered mainly due to 'after physicians suggestion' in 22 cases (36.1%) and 'for ease of administration' in 17 cases (27.9%). In group 2, the patients were not readministered mainly due to economic reasons in 21 cases (42%), unconcerning to osteoporosis in 14 cases (28%). CONCLUSIONS: This study shows 'doctor's suggestion' and 'ease of administration' could enhance drug adherence.