Prediction of Type of Proximal Femur Fracture by Analysis of Serum Makers / 대한골다공증학회지
Journal of Korean Society of Osteoporosis
;
: 31-35, 2015.
Article
in Korean
| WPRIM
| ID: wpr-760836
ABSTRACT
PURPOSE:
To analyze serum markers in proximal femur fracture patients, which are known to be accompanied with osteophorosis or metabolic diseases, and consider it as predictive factor and to study how it affects on the fracture form. MATERIALS ANDMETHODS:
Vit. D3 known as serum marker of Vit. D, 25(OH)D, and 1,25(OH)2D of 152 patients from April, 2013 to March, 2014 who visited our hospital and diagnosed as proximal femur fracture(Femur neck fracture 73, Intertrochanteric fracture 79) were analyzed. Also, serum calcium level corrected by serum protein, phosphate, creatinine, alkaline phosphatase, estradiol, IGF-1, and PTH were compared and analyzed.RESULTS:
Femur neck fracture group showed significantly low value of D3, 25(OH)D, and 1,25(OH)2D (P-value<0.05) as the values were 37.72+/-7.21 pg/mL, 27.05+/-8.43 ng/mL, 25.05+/-6.78 pg/mL in femur neck fracture group, and 40.36+/-6.97 pg/mL, 29.54+/-9.12 ng/mL, 28.87+/-7.43 pg/mL in intertrochanteric fracture group respectively. The number of patients who were diagnosed as hypovitaminosis D. due to serum 25(OH)D value lower than 30ng/ml were significantly high in femur neck fracture group as the numbers were 56 in femur neck fracture, and 44 in intertrochanteric fracture. Serum calcium level corrected by serum protein, phosphate, creatinine, alkaline phosphatase, estradiol, IGF-1 and PTH level showed no significant difference between two groups.CONCLUSION:
Serum 25(OH)D level was decreased in proximal femur fracture patiens, and was lower as the patient was older and BMD was lower. Therefore it is thought that proximal femur fracture is affected by vitamin D metabolism.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Vitamin D
/
Insulin-Like Growth Factor I
/
Biomarkers
/
Calcium
/
Creatinine
/
Alkaline Phosphatase
/
Estradiol
/
Femoral Neck Fractures
/
Femur
/
Metabolic Diseases
Type of study:
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Journal of Korean Society of Osteoporosis
Year:
2015
Type:
Article
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