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Initial Seizure Threshold in Brief-Pulse Bilateral Electroconvulsive Therapy in Patients with Schizophrenia or Schizoaffective Disorder
Psychiatry Investigation ; : 704-712, 2019.
Article in English | WPRIM | ID: wpr-760977
ABSTRACT

OBJECTIVE:

The present study aimed to report the initial seizure threshold (IST) of a brief-pulse bilateral electroconvulsive therapy (BP-BL ECT) in Korean patients with schizophrenia/schizoaffective disorder and to identify IST predictors.

METHODS:

Among 67 patients who received ECT and diagnosed with schizophrenia/schizoaffective disorder based on the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision, we included 56 patients who received 1-millisecond BP-BL ECT after anesthesia with sodium thiopental between March 2012 and June 2018. Demographic and clinical information was gathered from electronic medical records, and a multiple regression analysis was conducted to identify predictors of the IST.

RESULTS:

The mean age of the patients was 36.9±12.0 years and 30 (53.6%) patients were male. The mean and median IST were 105.9±54.5 and 96 millicoulombs (mC), respectively. The IST was predicted by age, gender, and dose (mg/kg) of sodium thiopental. Other physical and clinical variables were not associated with the IST.

CONCLUSION:

The present study demonstrated that the IST of 1-ms BP-BL ECT following sodium thiopental anesthesia in Korean patients was comparable to those reported in previous literature. The IST was associated with age, gender, and dose of sodium thiopental.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Psychotic Disorders / Schizophrenia / Seizures / Sodium / Thiopental / Diagnostic and Statistical Manual of Mental Disorders / Electroconvulsive Therapy / Electronic Health Records / Anesthesia Type of study: Practice guideline / Prognostic study Limits: Humans / Male Language: English Journal: Psychiatry Investigation Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Psychotic Disorders / Schizophrenia / Seizures / Sodium / Thiopental / Diagnostic and Statistical Manual of Mental Disorders / Electroconvulsive Therapy / Electronic Health Records / Anesthesia Type of study: Practice guideline / Prognostic study Limits: Humans / Male Language: English Journal: Psychiatry Investigation Year: 2019 Type: Article