Initial Seizure Threshold in Brief-Pulse Bilateral Electroconvulsive Therapy in Patients with Schizophrenia or Schizoaffective Disorder
Psychiatry Investigation
;
: 704-712, 2019.
Article
in English
| WPRIM
| ID: wpr-760977
ABSTRACT
OBJECTIVE:
The present study aimed to report the initial seizure threshold (IST) of a brief-pulse bilateral electroconvulsive therapy (BP-BL ECT) in Korean patients with schizophrenia/schizoaffective disorder and to identify IST predictors.METHODS:
Among 67 patients who received ECT and diagnosed with schizophrenia/schizoaffective disorder based on the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision, we included 56 patients who received 1-millisecond BP-BL ECT after anesthesia with sodium thiopental between March 2012 and June 2018. Demographic and clinical information was gathered from electronic medical records, and a multiple regression analysis was conducted to identify predictors of the IST.RESULTS:
The mean age of the patients was 36.9±12.0 years and 30 (53.6%) patients were male. The mean and median IST were 105.9±54.5 and 96 millicoulombs (mC), respectively. The IST was predicted by age, gender, and dose (mg/kg) of sodium thiopental. Other physical and clinical variables were not associated with the IST.CONCLUSION:
The present study demonstrated that the IST of 1-ms BP-BL ECT following sodium thiopental anesthesia in Korean patients was comparable to those reported in previous literature. The IST was associated with age, gender, and dose of sodium thiopental.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Psychotic Disorders
/
Schizophrenia
/
Seizures
/
Sodium
/
Thiopental
/
Diagnostic and Statistical Manual of Mental Disorders
/
Electroconvulsive Therapy
/
Electronic Health Records
/
Anesthesia
Type of study:
Practice guideline
/
Prognostic study
Limits:
Humans
/
Male
Language:
English
Journal:
Psychiatry Investigation
Year:
2019
Type:
Article
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