Opsoclonus-Myoclonus Syndrome Associated with Scrub Typhus / 대한평형의학회지
Journal of the Korean Balance Society
;
: 34-37, 2017.
Article
in Korean
| WPRIM
| ID: wpr-761229
ABSTRACT
Scrub typhus is an infective acute febrile disorder caused by the intracellular parasite Orientia tsutsugamushi. Neurological manifestations of scrub typhus are meningoencephalitis, cerebellitis, transverse myelitis, papilledema, and cranial nerve palsy. However, opsoclonus-myoclonus syndrome associated with scrub typhus has been rarely reported. A 59-year-old man developed vertigo, nausea, vomiting, and imbalance following scrub typhus infection for eight days. Examination showed eschar at the axilla, decreased mentality, and opsoclonus-myoclonus syndrome. Video-oculography disclosed opsoclonus with an amplitude of 15°–20° and a frequency of 6–8 Hz. The serum antibody titers to Orientia tsutsugamushi were 15,120, and cerebrospinal fluid analysis revealed pleocytosis. Brain magnetic resonance imaging was normal. Neurological symptoms and signs completely improved by systemic steroid and antibiotics treatment. Various mechanisms including direct disseminating inflammation or indirect immune modulation may give rise to neurological complications following scrub typhus.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Parasites
/
Orientia tsutsugamushi
/
Axilla
/
Vomiting
/
Brain
/
Scrub Typhus
/
Magnetic Resonance Imaging
/
Ocular Motility Disorders
/
Cerebrospinal Fluid
/
Papilledema
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Balance Society
Year:
2017
Type:
Article
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