The efficacy of selective nerve root block for the long-term outcome of postherpetic neuralgia
The Korean Journal of Pain
;
: 215-222, 2019.
Article
in English
| WPRIM
| ID: wpr-761696
ABSTRACT
BACKGROUND:
Several nerve blocks can reduce the incidence of postherpetic neuralgia (PHN) as well as relieve acute zoster-related pain, but the long-term outcome of PHN has not been clearly determined. This study investigated the efficacy of selective nerve root block (SNRB) for herpes zoster (HZ) on the long-term outcome of PHN.METHODS:
We prospectively conducted an interview of patients who had undergone an SNRB for HZ from January 2006 to December 2016 to evaluate their long-term PHN status. The relationship between the time from HZ onset to the first SNRB and the long-term outcome of PHN was investigated.RESULTS:
The data of 67 patients were collected. The patients were allocated to acute (SNRB ≤ 14 days, n = 16) or subacute (SNRB > 14 days, n = 51) groups. The proportions of cured patients were 62.5% and 25.5% in the acute and subacute groups (P = 0.007), respectively. In logistic regression, an SNRB >14 days was the significant predictor of PHN (adjusted odd ratio, 3.89; 95% confidence interval, 1.02–14.93; P = 0.047). Kaplan–Meier analysis revealed that time from the SNRB to the cure of PHN was significantly shorter in the acute group (2.4 ± 0.7 yr) than in the subacute group (5.0 ± 0.4 yr; P = 0.003).CONCLUSIONS:
An early SNRB during the acute stage of HZ (within 14 days) appears to decrease the incidence and shorten the duration of PHN, with a median of 5.0 years of follow-up.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Logistic Models
/
Incidence
/
Prospective Studies
/
Follow-Up Studies
/
Neuralgia, Postherpetic
/
Ganglia, Spinal
/
Herpes Zoster
/
Nerve Block
Type of study:
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
The Korean Journal of Pain
Year:
2019
Type:
Article
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