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A suspected sugammadex-induced anaphylactic shock: A case report
Anesthesia and Pain Medicine ; : 294-298, 2019.
Article in English | WPRIM | ID: wpr-762273
ABSTRACT

BACKGROUND:

The reversal of a neuromuscular blockade has typically been achieved with a cholinesterase inhibitor and the concomitant use of an anticholinergic agent, and this remains a popular method. Since the introduction of sugammadex in the market, its use has been increasing because of the rapid recovery from a neuromuscular blockade achieved by rocuronium. The occurrence of anaphylaxis or an anaphylactic reaction resulting from sugammadex is rare and has been reported sparsely. Thus, one may not recognize the possibility of sugammadex-induced hypersensitivity when sudden life-threatening hypotension occurs, especially without skin manifestations during the emergence of anesthesia. This may delay treatment and increase morbidity. CASE We report a case of a sugammadex-related hypersensitivity reaction which manifested as pure cardiovascular collapse during the emergence of anesthesia.

CONCLUSIONS:

We emphasize that vigilance should be paid for at least five minutes following sugammadex administration in daily clinical practice.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Skin Manifestations / Cholinesterases / Neuromuscular Blockade / Hypersensitivity / Hypotension / Anaphylaxis / Anesthesia / Methods Language: English Journal: Anesthesia and Pain Medicine Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Skin Manifestations / Cholinesterases / Neuromuscular Blockade / Hypersensitivity / Hypotension / Anaphylaxis / Anesthesia / Methods Language: English Journal: Anesthesia and Pain Medicine Year: 2019 Type: Article