Effect of severe contralateral carotid stenosis or occlusion on early and late outcomes after carotid endarterectomy
Annals of Surgical Treatment and Research
;
: 202-209, 2019.
Article
in English
| WPRIM
| ID: wpr-762702
ABSTRACT
PURPOSE:
We aimed to compare clinical outcomes after carotid endarterectomy (CEA) between Korean patients with and without severe contralateral extracranial carotid stenosis or occlusion (SCSO).METHODS:
Between January 2004 and December 2014, a total of 661 patients who underwent 731 CEAs were stratified by SCSO (non-SCSO and SCSO groups) and analyzed retrospectively. The study outcomes included the occurrence of major adverse cardiovascular events (MACE), defined as stroke or myocardial infarction, and all-cause mortality during the perioperative period and within 4 years after CEA.RESULTS:
There were no significant differences in the incidence of MACE or any individual MACE manifestations between the 2 groups during the perioperative period or within 4 years after CEA. On multivariate analysis to identify clinical variables associated with long-term study outcomes, older age (hazard ratios [HRs], 1.06; 95% confidence intervals [CIs], 1.03–1.09; P < 0.001) and diabetes mellitus (HR, 1.71; 95% CI, 1.14–2.57; P = 0.010) were significantly associated with an increased risk of MACE occurrence, while preexisting SCSO was not associated with long-term incidence of MACE and individual MACE components. Kaplan-Meier survival analysis showed similar MACE-free (P = 0.509), overall (P = 0.642), and stroke-free (P = 0.650) survival rates in the 2 groups.CONCLUSION:
There were no significant differences in MACE incidence after CEA between the non-SCSO and SCSO groups, and preexisting SCSO was not associated with an increased risk of perioperative or long-term MACE occurrence.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Incidence
/
Multivariate Analysis
/
Survival Rate
/
Retrospective Studies
/
Mortality
/
Endarterectomy, Carotid
/
Carotid Stenosis
/
Stroke
/
Diabetes Mellitus
/
Perioperative Period
Type of study:
Incidence study
/
Observational study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Annals of Surgical Treatment and Research
Year:
2019
Type:
Article
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