Development of Protocol for Korean Lung Cancer Screening Project (K-LUCAS) to Evaluate Effectiveness and Feasibility to Implement National Cancer Screening Program / Journal of the Korean Cancer Association, 대한암학회지
Cancer Research and Treatment
;
: 1285-1294, 2019.
Article
in English
| WPRIM
| ID: wpr-763231
ABSTRACT
PURPOSE:
To reduce lung cancer mortality, lung cancer screening was recommended using low-dose computed tomography (LDCT) to high-risk population. A protocol for multicenter lung cancer screening pilot project was developed to evaluate the effectiveness and feasibility of lung cancer screening to implement National Cancer Screening Program in Korea. MATERIALS ANDMETHODS:
Multidisciplinary expert committee was comprised to develop a standardized protocol for Korean Lung Cancer Screening Project (K-LUCAS). K-LUCAS is a population-based single arm trial that targets high-risk population aged 55-74 years with at least 30 pack-year smoking history. LDCT results are reported by Lung-RADS suggested by American Radiology Society. Network-based system using computer-aided detection program is prepared to assist reducing diagnostic errors. Smoking cessation counselling is provided to all currently smoking participants. A small pilot test was conducted to check the feasibility and compliance of the protocols for K-LUCAS.RESULTS:
In pilot test, 256 were participated. The average age of participants was 63.2 years and only three participants (1.2%) were female. The participants had a smoking history of 40.5 pack-year on average and 53.9% were current smokers. Among them, 86.3% had willing to participate in lung cancer screening again. The average willingness to quit smoking among current smokers was 12.7% higher than before screening. In Lung-RADS reports, 10 (3.9%) were grade 3 and nine (3.5%) were grade 4. One participant was diagnosed as lung cancer.CONCLUSION:
The protocol developed by this study is assessed to be feasible to perform K-LUCAS in multicenter nationwide scale.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arm
/
Smoke
/
Smoking
/
Pilot Projects
/
Mass Screening
/
Mortality
/
Smoking Cessation
/
Compliance
/
Diagnostic Errors
/
Early Detection of Cancer
Type of study:
Controlled clinical trial
/
Diagnostic study
/
Evaluation studies
/
Practice guideline
/
Prognostic study
/
Screening study
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Cancer Research and Treatment
Year:
2019
Type:
Article
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