Reactive Oxygen Species Modulator 1 (ROMO1), a New Potential Target for Cancer Diagnosis and Treatment / 전남의대학술지
Chonnam Medical Journal
;
: 136-143, 2019.
Article
in English
| WPRIM
| ID: wpr-763292
ABSTRACT
Today, the incidence of cancer in the world is rising, and it is expected that in the next several decades, the number of people suffering from cancer or (the cancer rate) will double. Cancer is defined as the excessive and uncontrolled growth of cells; of course (in simple terms), cancer is considered to be a set of other diseases that ultimately causes normal cells to be transformed into neoplastic cells. One of the most important causes of the onset and exacerbation of cancer is excessive oxidative stress. One of the most important proteins in the inner membrane of mitochondria is Reactive Oxygen Species (ROS) Modulator 1 (ROMO1) that interferes with the production of ROS, and with increasing the rate of this protein, oxidative stress will increase, which ultimately leads to some diseases, especially cancer. In this overview, we use some global databases to provide information about ROMO1 cellular signaling pathways, their related proteins and molecules, and some of the diseases associated with the mitochondrial protein, especially cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Incidence
/
Reactive Oxygen Species
/
Oxidative Stress
/
Mitochondrial Proteins
/
Diagnosis
/
Membranes
/
Mitochondria
Type of study:
Diagnostic study
/
Incidence study
/
Prognostic study
Language:
English
Journal:
Chonnam Medical Journal
Year:
2019
Type:
Article
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