Identification of Radioactive Iodine Refractory Differentiated Thyroid Cancer / 전남의대학술지
Chonnam Medical Journal
;
: 127-135, 2019.
Article
in English
| WPRIM
| ID: wpr-763293
ABSTRACT
Most differentiated thyroid cancer (DTC) patients have an excellent prognosis. However, about one-third of DTC patients with recurrent or metastatic disease lose the hallmark of specific iodine uptake initially or gradually and acquire radioactive iodine-refractory DTC (RAIR-DTC) with poor prognosis. Due to the potentially severe complications from unnecessarily repeated RAI therapy and encouraging progress of multiple targeted drugs for advanced RAIR-DTC patients, it has become crucial to identify RAIR-DTC early. In this review, we focus on the progress and controversies regarding the defining of RAIR-DTC, further with subsistent approaches and promising molecular nuclear medicine imaging in identifying RAIR-DTC, which may shed light on the proper management methodsof such patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Thyroid Gland
/
Thyroid Neoplasms
/
Molecular Imaging
/
Iodine
/
Iodine Radioisotopes
/
Nuclear Medicine
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Chonnam Medical Journal
Year:
2019
Type:
Article
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