The Utility of Endoscopic Ultrasound in Patients with Isolated Elevations in Serum Amylase and/or Lipase
Clinical Endoscopy
; : 175-181, 2019.
Article
in En
| WPRIM
| ID: wpr-763411
Responsible library:
WPRO
ABSTRACT
BACKGROUND/AIMS: The aim of this study was to describe the diagnostic yield of endoscopic ultrasound (EUS) in patients with isolated elevated levels of amylase and/or lipase. METHODS: A retrospective chart review was conducted at a large academic medical center from 2000 to 2016. Patients were selected based on having elevated amylase, lipase, or both, but without a diagnosis of pancreatitis or known pancreatobiliary disease. Patients were excluded if they had abnormal liver function tests or abnormal imaging of the pancreas. RESULTS: Of 299 EUS procedures performed, 38 met inclusion criteria. Symptoms were present in 31 patients, most frequently abdominal pain (87%). In 20 patients (53%), initial EUS most commonly found chronic pancreatitis (n=7; 18%), sludge (5; 13%), or new diagnosis of pancreas divisum (3; 8%). In the asymptomatic patients (7), 3 had a finding on EUS, most importantly sludge (2), stone (1), and pancreas divisum (1). No patients were diagnosed with a mass or pancreatic cyst. During the follow up period, 6 patients (22%) had cholecystectomy. CONCLUSIONS: In our study of patients with isolated elevations in amylase and/or lipase without acute pancreatitis who underwent EUS, approximately 50% had a pancreatobiliary finding, most commonly chronic pancreatitis or biliary sludge.
Key words
Full text:
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Index:
WPRIM
Main subject:
Pancreas
/
Pancreatic Cyst
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Pancreatitis
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Sewage
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Bile
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Cholecystectomy
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Abdominal Pain
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Retrospective Studies
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Follow-Up Studies
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Ultrasonography
Type of study:
Diagnostic_studies
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Observational_studies
/
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Clinical Endoscopy
Year:
2019
Type:
Article