Efficacy of Nasobiliary Tubes and Biliary Stents in Management of Patients with Bile Leak after Liver Transplantation: A Systematic Review
Clinical Endoscopy
;
: 159-167, 2019.
Article
in English
| WPRIM
| ID: wpr-763413
ABSTRACT
BACKGROUND/AIMS:
Bile leak is one of the most common complications of liver transplantation. The treatment options for bile leaks include conservative management, surgical re-intervention, percutaneous drainage and endoscopic drainage. We aimed to perform a systematic review to identify the efficacy of endoscopic treatment in the resolution of post-transplant bile leaks.METHODS:
Two independent reviewers performed systematic literature search in PubMed, ISI Web of Science, grey literature and relevant references in May 2017. Human studies in English with documented post-liver transplant bile leaks were included.RESULTS:
Thirty-four studies were included in the final analysis. The pooled efficacy of biliary stents for the resolution of post-transplant bile leaks was 82.43% compared with 87.15% efficacy of nasobiliary tubes. The efficacy of biliary stents was lower for anastomotic leaks (69.23%) compared to T-tube (90.9%) or cut-surface/ cystic duct stump related leaks (92.8%). Similarly, the efficacy of nasobiliary tube was also lower for anastomotic leaks (58.33%) compared to T-tube or cut-surface related leaks (100%).CONCLUSIONS:
In this systematic review, the overall efficacy was 82.43% in biliary stent group, and 87.15% in nasobiliary tube group. Both biliary stent and nasobiliary tube were more effective in managing non-anastomotic leaks compared to anastomotic leaks.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Bile
/
Stents
/
Drainage
/
Biliary Fistula
/
Liver Transplantation
/
Cystic Duct
/
Anastomotic Leak
/
Liver
Type of study:
Systematic reviews
Limits:
Humans
Language:
English
Journal:
Clinical Endoscopy
Year:
2019
Type:
Article
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