Neonatal Thrombocytopenia: Diagnostic Approach and Platelet Transfusion Guideline / 임상소아혈액종양
Clinical Pediatric Hematology-Oncology
;
: 67-76, 2019.
Article
in English
| WPRIM
| ID: wpr-763520
ABSTRACT
Neonatal thrombocytopenia, defined as platelet counts of less than 150,000/µL, is a frequent hematologic abnormality in neonatal period. Differential diagnosis of neonatal thrombocytopenia may be challenging to pediatric hematologists and neonatologists because neonatal thrombocytopenia is associated with diverse maternal or neonatal clinical conditions. An accurate diagnosis for neonatal thrombocytopenia will lead to appropriate evaluation and management. Platelet transfusion is the primary management of neonatal thrombocytopenia. Most thrombocytopenic newborns received platelet concentrates to prevent major hemorrhage or treat ongoing bleeding according to institutional policy. However, scientific evidences for benefit and consistent guideline for platelet transfusion in neonates are lacking, further investigation to establish the standard recommendation for platelet transfusion is needed. This article reviewed the diagnostic approach and current guideline for platelet transfusion management for neonatal thrombocytopenia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Platelet Count
/
Thrombocytopenia
/
Blood Platelets
/
Organizational Policy
/
Platelet Transfusion
/
Diagnosis
/
Diagnosis, Differential
/
Thrombocytopenia, Neonatal Alloimmune
/
Hemorrhage
Type of study:
Diagnostic study
/
Practice guideline
Limits:
Humans
/
Infant
/
Infant, Newborn
Language:
English
Journal:
Clinical Pediatric Hematology-Oncology
Year:
2019
Type:
Article
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