Efficacy of Asenapine in Schizophrenia Resistant to Clozapine Combined with Electroconvulsive Therapy: A Case Report
Clinical Psychopharmacology and Neuroscience
;
: 559-563, 2019.
Article
in English
| WPRIM
| ID: wpr-763562
ABSTRACT
Schizophrenic patients resistant to antipsychotics are diagnosed as having treatment-refractory schizophrenia, and they are treated with clozapine. However, clozapine is sometimes combined with electroconvulsive therapy (ECT) if clozapine monotherapy fails. In this report, a severe treatment-refractory schizophrenic patient who did not respond to clozapine even with ECT, but who recovered with asenapine monotherapy, is presented. Asenapine, considered a serotonin spectrum dopamine modulator, is a new atypical antipsychotic with unique pharmacological features that is used not only for schizophrenia, but also for bipolar disorder. The unique features of asenapine may be effective for some treatment-refractory schizophrenic patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Schizophrenia
/
Suicide
/
Antipsychotic Agents
/
Bipolar Disorder
/
Dopamine
/
Serotonin
/
Clozapine
/
Electroconvulsive Therapy
Limits:
Humans
Language:
English
Journal:
Clinical Psychopharmacology and Neuroscience
Year:
2019
Type:
Article
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