Association between Change in Alcohol Consumption and Metabolic Syndrome: Analysis from the Health Examinees Study
Diabetes & Metabolism Journal
;
: 615-626, 2019.
Article
in English
| WPRIM
| ID: wpr-763684
ABSTRACT
BACKGROUND:
The association between change in alcohol intake and metabolic syndrome is unclear.METHODS:
This retrospective cohort consisted of 41,368 males and females from the Health Examinees-GEM study. Participants were divided into non-drinkers (0.0 g/day), light drinkers (male 0.1 to 19.9 g/day; female 0.1 to 9.9 g/day), moderate drinkers (male 20.0 to 39.9 g/day; female 10.0 to 19.9 g/day), and heavy drinkers (male ≥40.0 g/day; female ≥20.0 g/day) for each of the initial and follow-up health examinations. Logistic regression analysis was used to determine the adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for developing metabolic syndrome according to the change in alcohol consumption between the initial and follow-up health examinations. Adjusted mean values for the change in waist circumference, fasting serum glucose (FSG), blood pressure, triglycerides, and high density lipoprotein cholesterol (HDL-C) levels were determined according to the change in alcohol consumption by linear regression analysis.RESULTS:
Compared to persistent light drinkers, those who increased alcohol intake to heavy levels had elevated risk of metabolic syndrome (aOR, 1.45; 95% CI, 1.09 to 1.92). In contrast, heavy drinkers who became light drinkers had reduced risk of metabolic syndrome (aOR, 0.61; 95% CI, 0.44 to 0.84) compared to persistent heavy drinkers. Increased alcohol consumption was associated with elevated adjusted mean values for waist circumference, FSG, blood pressure, triglycerides, and HDL-C levels (all P<0.05). Reduction in alcohol intake was associated with decreased waist circumference, FSG, blood pressure, triglycerides, and HDL-C levels among initial heavy drinkers (all P<0.05).CONCLUSION:
Heavy drinkers who reduce alcohol consumption could benefit from reduced risk of metabolic syndrome.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Triglycerides
/
Blood Glucose
/
Blood Pressure
/
Alcohol Drinking
/
Linear Models
/
Logistic Models
/
Odds Ratio
/
Retrospective Studies
/
Cohort Studies
/
Follow-Up Studies
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Diabetes & Metabolism Journal
Year:
2019
Type:
Article
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