Trifolium pratense induces apoptosis through caspase pathway in FaDu human hypopharynx squamous carcinoma cells
International Journal of Oral Biology
; : 81-88, 2019.
Article
in Ko
| WPRIM
| ID: wpr-764047
Responsible library:
WPRO
ABSTRACT
Trifolium pratense leaves (red clover) has been used in Oriental and European folk medicine for the treatment of whooping cough, asthma, and eczema, and is now being used to treat and alleviate the symptoms, such as hot flushes, cardiovascular health effects that occur in postmenopausal women. However, relatively little scientific data is available on the physiological activity of this plant. Therefore, in this study, we investigated the anti-cancer activity of T. pratense leaves using methanol extract of T. pratense leaves (MeTP) on human FaDu hypopharyngeal squamous carcinoma cells. MeTP inhibited the viability of FaDu cells by inducing apoptosis through the cleavage of procaspase-3,
Key words
Full text:
1
Index:
WPRIM
Main subject:
Plants
/
Asthma
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Mouth Neoplasms
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Carcinoma, Squamous Cell
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Down-Regulation
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Up-Regulation
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Whooping Cough
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Blotting, Western
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Apoptosis
/
Trifolium
Limits:
Female
/
Humans
Language:
Ko
Journal:
International Journal of Oral Biology
Year:
2019
Type:
Article