Alpha-1 Adrenergic Receptor Blockers for the Treatment of Lower Urinary Tract Symptoms in Women: A Systematic Review and Meta-Analysis / 대한배뇨장애요실금학회지
International Neurourology Journal
;
: 56-68, 2019.
Article
in English
| WPRIM
| ID: wpr-764098
ABSTRACT
PURPOSE:
To assess the effectiveness of alpha-1 adrenergic receptor blockers (α1-blockers) in the treatment of female lower urinary tract symptoms (LUTS).METHODS:
A literature search was conducted using the PubMed/MEDLINE, Embase, and Cochrane Library databases. Fourteen studies with 1,319 patients were ultimately included. The study comprised 2 analyses a comparison of urinary symptom scores, maximal flow rate (Qmax), and postvoid residual (PVR) urine volume before and after α1-blocker administration in 8 prospective, open-label studies and 5 randomized clinical trials (RCTs); and an evaluation of the same variables in α1-blocker and placebo groups in 4 RCTs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prospective Studies
/
Receptors, Adrenergic, alpha-1
/
Lower Urinary Tract Symptoms
Type of study:
Controlled clinical trial
/
Diagnostic study
/
Observational study
/
Systematic reviews
Limits:
Female
/
Humans
Language:
English
Journal:
International Neurourology Journal
Year:
2019
Type:
Article
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