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Primary Histiocytic Sarcoma Presenting as a Breast Mass: A Case Report / 한국유방암학회지
Journal of Breast Cancer ; : 491-496, 2019.
Article in English | WPRIM | ID: wpr-764273
ABSTRACT
Histiocytic sarcoma is a rare hematologic malignancy, with very few cases of primary histiocytic sarcoma of the breast described in English scientific literature. Herein, we describe a case of primary histiocytic sarcoma of the breast in a 75-year-old woman, with no clinical history of malignant tumors, who presented with a palpable solitary breast mass. Microscopically, the resected breast mass showed large pleomorphic cells, some multinucleated giant cells, and admixed inflammatory components. The pleomorphic tumor cells further showed a diffuse, noncohesive growth pattern, an abundant eosinophilic cytoplasm, and strong and diffuse immunoreactivity for cluster of differentiation (CD) 68 and CD163. Furthermore, a whole-body positron-emission tomography/computed tomography using deoxy-2-[¹⁸F]fluoro-D-glucose performed after surgery showed no other masses or lesions. After surgical excision, the patient was followed up, and no evidence of tumor recurrence or metastasis was noted.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Recurrence / Breast / Giant Cells / Hematologic Neoplasms / Cytoplasm / Eosinophils / Histiocytic Sarcoma / Histiocytes / Neoplasm Metastasis Limits: Aged / Female / Humans Language: English Journal: Journal of Breast Cancer Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Recurrence / Breast / Giant Cells / Hematologic Neoplasms / Cytoplasm / Eosinophils / Histiocytic Sarcoma / Histiocytes / Neoplasm Metastasis Limits: Aged / Female / Humans Language: English Journal: Journal of Breast Cancer Year: 2019 Type: Article