Primary Histiocytic Sarcoma Presenting as a Breast Mass: A Case Report / 한국유방암학회지
Journal of Breast Cancer
;
: 491-496, 2019.
Article
in English
| WPRIM
| ID: wpr-764273
ABSTRACT
Histiocytic sarcoma is a rare hematologic malignancy, with very few cases of primary histiocytic sarcoma of the breast described in English scientific literature. Herein, we describe a case of primary histiocytic sarcoma of the breast in a 75-year-old woman, with no clinical history of malignant tumors, who presented with a palpable solitary breast mass. Microscopically, the resected breast mass showed large pleomorphic cells, some multinucleated giant cells, and admixed inflammatory components. The pleomorphic tumor cells further showed a diffuse, noncohesive growth pattern, an abundant eosinophilic cytoplasm, and strong and diffuse immunoreactivity for cluster of differentiation (CD) 68 and CD163. Furthermore, a whole-body positron-emission tomography/computed tomography using deoxy-2-[¹⁸F]fluoro-D-glucose performed after surgery showed no other masses or lesions. After surgical excision, the patient was followed up, and no evidence of tumor recurrence or metastasis was noted.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Breast
/
Giant Cells
/
Hematologic Neoplasms
/
Cytoplasm
/
Eosinophils
/
Histiocytic Sarcoma
/
Histiocytes
/
Neoplasm Metastasis
Limits:
Aged
/
Female
/
Humans
Language:
English
Journal:
Journal of Breast Cancer
Year:
2019
Type:
Article
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