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Impact of Depression on Medication Adherence of Patients with Systemic Lupus Erythematosus: Focusing on Mediating Effect of Self-Efficacy and Belief about Medication / 임상간호연구
Journal of Korean Clinical Nursing Research ; (3): 170-178, 2019.
Article in Korean | WPRIM | ID: wpr-764763
ABSTRACT

PURPOSE:

The purpose of this study was to determine the mediating effects of self-efficacy and the belief about medication on the association between depression and medication adherence in patients with systemic lupus erythematosus.

METHODS:

128 patients aged ≥19 years, who were regular outpatients or admitted patients diagnosed with systemic lupus erythematosus at a tertiary hospital in B city, participated in this study. Data were collected by using a self-administered questionnaire. Testing of mediating effects was analyzed by a parallel redundant mediated model using the PROCESS macro for SPSS version 3.3.

RESULTS:

They scored an average of 16.71±11.13 for depression, 694.14±170.68 for self-efficacy, 3.05±4.60 for the belief about medication, and 90.14±15.37 for medication adherence. The direct effect of depression on medication adherence was not statistically significant, but the indirect effects of depression mediated with self-efficacy and belief about medication were statistically significant.

CONCLUSION:

It is necessary to develop and apply a nursing intervention program that can not only relieve depression but also promote self-efficacy and the belief about medication with the objective of improving medication adherence among patients with systemic lupus erythematosus.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Outpatients / Nursing / Negotiating / Depression / Medication Adherence / Tertiary Care Centers / Lupus Erythematosus, Systemic Type of study: Prognostic study Limits: Humans Language: Korean Journal: Journal of Korean Clinical Nursing Research Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Outpatients / Nursing / Negotiating / Depression / Medication Adherence / Tertiary Care Centers / Lupus Erythematosus, Systemic Type of study: Prognostic study Limits: Humans Language: Korean Journal: Journal of Korean Clinical Nursing Research Year: 2019 Type: Article