Cold Allodynia after C2 Root Resection in Sprague-Dawley Rats
Journal of Korean Neurosurgical Society
;
: 186-193, 2018.
Article
in English
| WPRIM
| ID: wpr-765245
ABSTRACT
OBJECTIVE:
The purpose of this study was to evaluate pain-related behaviors after bilateral C2 root resection and change in pain patterns in the suboccipital region in rats.METHODS:
Male Sprague-Dawley rats were randomly assigned to three groups (n=25/group); näive, sham, and C2 resection. Three, 7, 10, and 14 days after surgery, cold allodynia was assessed using 20 μL of 99.7% acetone. c-Fos and c-Jun were immunohistochemically stained to evaluate activation of dorsal horn gray matter in C2 segments of the spinal cord 2 hours, 1 day, 7 days, and 14 days after surgery.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Acetone
/
Spinal Cord
/
Rats, Sprague-Dawley
/
Gray Matter
/
Spinal Cord Dorsal Horn
/
Hyperalgesia
/
Neuralgia
/
Neurons
Limits:
Animals
/
Humans
/
Male
Language:
English
Journal:
Journal of Korean Neurosurgical Society
Year:
2018
Type:
Article
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