Hashimoto's Encephalopathy with Reversible Diffuse Leukoencephalopathy
Journal of Neurocritical Care
;
(2): 54-57, 2018.
Article
in English
| WPRIM
| ID: wpr-765894
ABSTRACT
BACKGROUND:
The magnetic resonance imaging (MRI) findings of Hashimoto's encephalopathy (HE) are variable; images range from having a normal appearance, to showing ischemic lesions, demyelination, or vasogenic edema. CASE REPORT A 57-year-old woman presented with a sudden onset of dysarthria and dizziness. Routine blood tests were normal and the MRI was unremarkable. After admission, she developed aphasic seizures and myoclonus, and eventually became comatose. A follow up MRI showed diffuse high signal intensities at the bilateral cerebral white matter on fluid attenuated inversion recovery imaging. The serum titers of the anti-thyroglobulin antibody and anti-thyroperoxidase antibody were increased. After 5 days of 1,000 mg/day of intravenous methylprednisolone infusion, she recovered rapidly.CONCLUSION:
We propose that repeated brain MRIs are necessary for the diagnosis of HE. Diffuse leukoencephalopathy may be a pathologic finding on MRI and, in this case study, was shown to be reversible after applying an appropriate treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Seizures
/
Brain
/
Brain Diseases
/
Methylprednisolone
/
Magnetic Resonance Imaging
/
Follow-Up Studies
/
Demyelinating Diseases
/
Coma
/
Diagnosis
/
Dizziness
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Female
/
Humans
Language:
English
Journal:
Journal of Neurocritical Care
Year:
2018
Type:
Article
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