A Retrospective Analysis of Eight Cases of Merkel Cell Carcinoma
Archives of Craniofacial Surgery
; : 41-45, 2013.
Article
in En
| WPRIM
| ID: wpr-7659
Responsible library:
WPRO
ABSTRACT
BACKGROUND: Merkel cell carcinoma (MCC) is a rare locally aggressive cutaneous neuroendocrine carcinoma with a high incidence of local recurrence, regional lymph node metastasis, followed by distant metastasis. Because of shortage of the retrospective study, standard treatment has not been established. The purpose of this study was to present the surgical treatment and outcome of 8 patients with MCC. METHODS: We report our experiences with 8 patients who underwent treatment for MCC at our institution from 2000 through 2012. Two men and 6 women received treatment for MCC. The mean age was 76.4 years (range, 53 to 93 years). RESULTS: The follow-up period ranged from 7 to 26 months (mean, 22.9). During the follow-up period, three of 8 patients had a relapse (mean time before recurrence, 10 months; 1 month, 7 months, and 22 months). After primary surgery, 3 patients underwent radiotherapy, and 1 patient received chemotherapy. CONCLUSION: MCC is an aggressive skin cancer with a high rate of local recurrence. Complete surgical excision is the mainstay of local treatment, but adjuvant radiotherapy should be considered for better local control.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Recurrence
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Skin Neoplasms
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Carcinoma, Merkel Cell
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Incidence
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Retrospective Studies
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Follow-Up Studies
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Carcinoma, Neuroendocrine
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Radiotherapy, Adjuvant
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Disease Management
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Lymph Nodes
Type of study:
Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limits:
Female
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Humans
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Male
Language:
En
Journal:
Archives of Craniofacial Surgery
Year:
2013
Type:
Article