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Pharmacological treatment of chronic constipation: focused on oral laxatives
Journal of the Korean Medical Association ; : 57-61, 2018.
Article in Korean | WPRIM | ID: wpr-766442
ABSTRACT
Chronic constipation is a common functional gastrointestinal disorder that may have a significant impact on the quality of life of affected individuals. If dietary and lifestyle modifications are not successful, pharmacological interventions should be used to manage chronic constipation. The first-line conventional laxatives include bulk-forming, osmotic, and stimulant laxatives. If chronic constipation is refractory to conventional laxatives, prucalopride should be considered. The choice of a laxative should be made based on a consideration of the treatment duration, dosing schedule, type of agent, effects, and side effects of the agent, as well as cost-effectiveness. An individualized approach is needed according to the patient's underlying disease and clinical condition.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Appointments and Schedules / Quality of Life / Constipation / Laxatives / Gastrointestinal Diseases / Life Style Language: Korean Journal: Journal of the Korean Medical Association Year: 2018 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Appointments and Schedules / Quality of Life / Constipation / Laxatives / Gastrointestinal Diseases / Life Style Language: Korean Journal: Journal of the Korean Medical Association Year: 2018 Type: Article