Pathophysiology and new treatment of itch
Journal of the Korean Medical Association
;
: 670-677, 2018.
Article
in Korean
| WPRIM
| ID: wpr-766461
ABSTRACT
Many of the patients visit the doctors because of itching sensation. Itching is an unpleasant sensation. In the epidermal keratinocytes, various neurotransmitters and receptors are related itching. The itch signal is mainly transmitted through the lateral spinal ganglion-derived nerve fibers extending to the lower epidermis. Many mediators such as histamine are involved in the itching pathway. It can be helpful in the treatment of patients having itching sensation with a lot of new therapies from the basic medication such as antihistamines. Also, many drugs are currently under study.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pruritus
/
Sensation
/
Histamine
/
Keratinocytes
/
Neurotransmitter Agents
/
Epidermis
/
Histamine Antagonists
/
Nerve Fibers
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Medical Association
Year:
2018
Type:
Article
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