Diagnosis and treatment of latent tuberculosis infection
Journal of the Korean Medical Association
;
: 11-17, 2019.
Article
in Korean
| WPRIM
| ID: wpr-766545
ABSTRACT
In order to eliminate tuberculosis worldwide by 2050, effective management of latent tuberculosis infection is essential, and policy-makers have begun to recognize the importance of scaling up preventive therapy. The current guideline recommends targeted latent tuberculosis infection testing that identifies high-risk groups based on risk stratification for progression from latent infection to active disease. Both the tuberculin skin test and interferon-gamma releasing assay have a similar diagnostic efficacy for predicting progression to active tuberculosis. The Korean guideline recommends 9-month isoniazid monotherapy as the standard treatment; however, more evidence supports that short course rifampicin-based regimen is both more effective and tolerable than isoniazid monotherapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tuberculin
/
Tuberculosis
/
Skin Tests
/
Interferon-gamma
/
Diagnosis
/
Latent Tuberculosis
/
Interferon-gamma Release Tests
/
Isoniazid
Type of study:
Diagnostic study
/
Practice guideline
/
Prognostic study
Language:
Korean
Journal:
Journal of the Korean Medical Association
Year:
2019
Type:
Article
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