Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP) with Novel CSF1R Mutation
Journal of the Korean Neurological Association
; : 408-413, 2019.
Article
in Ko
| WPRIM
| ID: wpr-766813
Responsible library:
WPRO
ABSTRACT
Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a subtype of dominantly inherited leukoencephalopathies caused by novel CSF1R gene mutation predominantly affecting the cerebral white matter. High signal lesions on diffusion weighted image (DWI) are characteristic. Herein, we describe a patent with ALSP with a novel mutation. The patient had persistent DWI lesions, worsening white matter changes associated with rapidly progressive clinical symptoms.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Axons
/
Neuroglia
/
Diffusion
/
Leukoencephalopathies
/
White Matter
Limits:
Humans
Language:
Ko
Journal:
Journal of the Korean Neurological Association
Year:
2019
Type:
Article