Malignant Fibrous Histiocytoma: A Case report / 대한정형외과학회잡지

ABSTRACT

A case of malignant fibrous histiocytoma in the right thigh is reported together with a brief review of literature in this paper. This tumor characteristically consists of a solitary circumscribed and firm mass 5 × 5 × 4cm in dimension, which has originated in the deep soft tissues. Wide local excision has been the most common form of treatment for this lesion, after open biopsy has been performed for the diagnosis. Microscopically, there is a pattern of histiocytes and bizarre histiocytic giant cells intermingled in a fibrous stroma with fibroblasts arranged in storiform pattern. Foam cells and abnormal mitoses are also frequently found in this tumor. Local recurrence is common. Metastasis is less common but with metastasis the prognosis is poor. In this case local recurrence was noted two months after excisional biopsy but metastasis was not occurred.