A study on microangiography of induced breast carcinoma in rats (I)
Journal of the Korean Radiological Society
;
: 366-370, 1984.
Article
in Korean
| WPRIM
| ID: wpr-770404
ABSTRACT
Microangiography is a very effective method in evaluating morphological changes of small vessels not onlybecause it shows subtle changes in microvasculature but also shows whole length of the vessels. Reccently many experimental studies on microagniography of normal and injured tissues are reported, but there's no report on microangiography of artificially induced cancer tissue. Authors artificially induced breast carinoma in rats withintravenous infusion of carcinogenic substance, N-methyl-N-Nitrosourea, and microangiography was done to evaluate vascularity and morphological changes of vessels of the cancer tissue. The results are as follows; 1.Distribtution of the tumor vessels showed tendency to form bolules. 2. Overall tumor vascularity was slightly hypervascular. 3. Variable sized, parallell arraged, tumor vessels surrounded the boundary of the lobules whilemore small vessels invaginated to the center of lobules in tortuous or straight fashion. 4. In overall, peripherayof the lobule was more vascular than center. 5. There was no evidence of cental tumor necrosis, and findings of extravasation of dye or venous lake formation were minimal. 6. Pathologically, the tumor tissue was well differentiated adenocarcinoma with tendency of lobule formation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Breast
/
Breast Neoplasms
/
Adenocarcinoma
/
Lakes
/
Microvessels
/
Methods
/
Methylnitrosourea
/
Necrosis
Limits:
Animals
Language:
Korean
Journal:
Journal of the Korean Radiological Society
Year:
1984
Type:
Article
Similar
MEDLINE
...
LILACS
LIS