Polyethylene Glycol (PEG-3350, Colyte) Poisoning due to Intra-Peritoneal Leakage in an Elderly Patient / 대한구급학회지
The Korean Journal of Critical Care Medicine
;
: 56-60, 2015.
Article
in English
| WPRIM
| ID: wpr-770845
ABSTRACT
Polyethylene glycol (PEG)-3350 is the most frequently used lavage solution for bowel cleansing prior to colonoscopy or elective surgery because its large molecular weight means that it is poorly absorbed. However, if it leaks into the peritoneal cavity, complications may arise. Few published studies have assessed the absorption, distribution, metabolism and excretion of PEG. Moreover, no published clinical data regarding complications due to the intra-peritoneal leakage of PEG-3350 could be found. We report on an elderly patient who developed the poisoning caused by leaking of PEG-3350 during bowel preparation. It resulted in severe metabolic acidosis, hypernatremia, hyperosmolality and a high anion gap, but it was effectively treated with early continuous renal replacement therapy after surgery.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peritoneal Cavity
/
Poisoning
/
Polyethylene Glycols
/
Acid-Base Equilibrium
/
Acidosis
/
Colonoscopy
/
Renal Replacement Therapy
/
Absorption
/
Hypernatremia
/
Therapeutic Irrigation
Limits:
Aged
/
Humans
Language:
English
Journal:
The Korean Journal of Critical Care Medicine
Year:
2015
Type:
Article
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