Baeyer-Villiger monooxygenases in the biosynthesis of microbial secondary metabolites / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 351-362, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-771371
ABSTRACT
Baeyer-Villiger monooxygenases, a well-studied class of flavin-dependent enzymes, catalyze the conversion of ketones to lactones or esters and the oxygenation of heteroatoms, which possesses great practical prospect in synthetic chemistry and biocatalysis. In this review, we focus on Baeyer-Villiger oxidations involved in biosynthesis of microbial secondary metabolites and discuss the characteristics of these Baeyer-Villiger oxidations and Baeyer-Villiger monooxygenases, to provide reference for the protein engineering of Baeyer-Villiger monooxygenases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oxidation-Reduction
/
Protein Engineering
/
Catalysis
/
Biocatalysis
/
Mixed Function Oxygenases
Language:
Chinese
Journal:
Chinese Journal of Biotechnology
Year:
2019
Type:
Article
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