Practical Application of Semiquantitative Procalcitonin Test in Emergency Department
Journal of the Korean Society of Emergency Medicine
;
: 665-671, 2008.
Article
in Korean
| WPRIM
| ID: wpr-77146
ABSTRACT
PURPOSE:
Procalcitonin (PCT) is a good marker of infection but is still not routinely used. Here, we assessed the usefulness of a semi-quantitative procalcitonin test kit (PCT-Q(R)), a rapid and simple test for evaluating sepsis in the emergency department.METHODS:
We recruited 80 patients who visited the emergency center and with systemic inflammatory response syndrome (SIRS). Patients were classified into 4 groups according to PCT levels using PCT-Q[Ed-Trademark signs only have to be given one time in a document]. Mortality rate, bacteremia, severity score, and severity of sepsis (SIRS/sepsis/severe sepsis/septic shock) were assessed with the criteria of the American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference. We calculated a receiver operating characteristic curve (ROC curve), cut-off value, and the related diagnostic parameters of each cut-off value.RESULTS:
Higher PCT levels were significantly associated with increased mortality, bacteremia, and severity scores. PCT levels could discriminate between sepsis and severe sepsis at a threshold of 2 ng/ml.CONCLUSION:
PCT-Q is a prognostic marker of infectious disease, but low levels do not always indicate a good prognosis. PCT levels increase with aggravation of sepsis, especially at values greater than 2 ng/ml for severe sepsis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Protein Precursors
/
Reagent Strips
/
Thorax
/
Calcitonin
/
Communicable Diseases
/
ROC Curve
/
Bacteremia
/
Systemic Inflammatory Response Syndrome
/
Sepsis
Type of study:
Practice guideline
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Society of Emergency Medicine
Year:
2008
Type:
Article
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