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A new eudesmane type sesquiterpene from cultivated Clerodendranthus spicatus in Hainan / 中国中药杂志
Article in Chinese | WPRIM | ID: wpr-771512
Responsible library: WPRO
ABSTRACT
Six compounds were isolated from the aerial part of cultivated Clerodendranthus spicatus in Hainan with various chromatographic techniques,and their structures were determined as1-dehydroxy-1-oxo-rupestrinol(1),N-trans-feruloyltyramine(2),methyl 3,4-dihydroxyphenyllactate(3),caffein acid(4),methyl caffeate(5) and ethyl caffeate(6),via analysis of physicochemical properties and spectroscopic evidence.Compound 1 was a new compound,while compounds 2 and 3 were isolated from C.spicatus for the first time.Biological activity results showed that compounds 2-4 exhibited α-glucosidase inhibitory activity with different inhibition ratio.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Molecular Structure / Chemistry / China / Lamiaceae / Sesquiterpenes, Eudesmane / Phytochemicals / Glycoside Hydrolase Inhibitors Country/Region as subject: Asia Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Molecular Structure / Chemistry / China / Lamiaceae / Sesquiterpenes, Eudesmane / Phytochemicals / Glycoside Hydrolase Inhibitors Country/Region as subject: Asia Language: Chinese Journal: China Journal of Chinese Materia Medica Year: 2019 Type: Article