Catalysis of enzymes under industrial environment and their adaptive modifications: a review / 生物工程学报
Chinese Journal of Biotechnology
; (12): 1857-1869, 2019.
Article
in Zh
| WPRIM
| ID: wpr-771747
Responsible library:
WPRO
ABSTRACT
Enzymes have a wide range of applications and great industrial potential. However, large-scale applications of enzymes are restricted by the harsh industrial environment, such as high temperature, strong acid/alkali, high salt, organic solvents, and high substrate concentration. Adaptive modification (such as rational or semi-rational design, directed evolution and immobilization) is the most common strategy to improve the catalysis of enzymes under industrial conditions. Here, we review the catalysis of enzymes in the industrial environment and various methods adopted for the adaptive modifications in recent years, to provide reference for the adaptive modifications of enzymes.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Pharmacology
/
Solvents
/
Biotechnology
/
Protein Engineering
/
Chemistry
/
Enzymes
/
Biocatalysis
/
Hot Temperature
/
Hydrogen-Ion Concentration
/
Metabolism
Language:
Zh
Journal:
Chinese Journal of Biotechnology
Year:
2019
Type:
Article